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Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 341-347 doi: 10.1007/s11684-011-0169-z

Abstract: Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML).

Keywords: acute promyelocytic leukemia     all-trans retinoic acid     arsenic trioxide    

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 909-918 doi: 10.1007/s11684-021-0890-1

Abstract: In patients with acute promyelocytic leukemia (APL), intracranial hemorrhage (ICH), if not identified

Keywords: acute promyelocytic leukemia     intracranial hemorrhage     cytokines     biomarker    

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 45-52 doi: 10.1007/s11684-011-0117-y

Abstract:

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia.

Keywords: acute promyelocytic leukemia     arsenic     all-trans retinoic acid     survival    

BRD4 interacts with PML/RARα in acute promyelocytic leukemia

Qun Luo, Wanglong Deng, Haiwei Wang, Huiyong Fan, Ji Zhang

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 726-734 doi: 10.1007/s11684-017-0604-x

Abstract: However, few studies have investigated whether BRD4 influenced acute promyelocytic leukemia (APL), andwhether BRD4 had interaction with promyelocytic leukemia-retinoic acid receptor α (PML/RARα) fusion

Keywords: BRD4     PML/RARα     APL     interaction    

network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acutepromyelocytic leukemia

Frontiers of Medicine doi: 10.1007/s11684-023-1022-x

Abstract: The treatment of PML/RARA+ acute promyelocytic leukemia (APL) with all-trans-retinoic acid and arsenic

Keywords: acute promyelocytic leukemia     plasma proteomics     plasma metabolomics     cross-sectional correlation network    

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acutepromyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: cyclin-dependent kinase inhibitors is a target of the PML/RARα oncofusion protein in leukemogenesis of acutepromyelocytic leukemia (APL).

Keywords: CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acutepromyelocytic leukemia

Dan Huang, Yan Yang, Jian Sun, Xiaorong Dong, Jiao Wang, Hongchen Liu, Chengquan Lu, Xueyu Chen, Jing Shao, Jinsong Yan

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 410-422 doi: 10.1007/s11684-017-0527-6

Abstract: heterotetramer (AIIt) associated with PML/RARα fusion protein causes lethal hyperfibrinolysis in acutepromyelocytic leukemia (APL), but the mechanism is unclear.To facilitate the investigation of regulatory association between ANXA2 and promyelocytic leukemia/retinoic

Keywords: annexin A2-S100A10 heterotetramer     PML/RARα fusion protein     plasmin     cell invasion     acute promyelocytic leukemia    

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 356-362 doi: 10.1007/s11684-010-0220-5

Abstract: Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell.

Keywords: acute myeloid leukemia     mutations     risk stratification    

Precision medicine in acute lymphoblastic leukemia

Ching-Hon Pui

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 689-700 doi: 10.1007/s11684-020-0759-8

Abstract: The cure rate of childhood acute lymphoblastic leukemia (ALL) has exceeded 90% in some contemporary clinical

Keywords: acute lymphoblastic leukemia     molecular therapeutics     targeted therapy     tyrosine kinase inhibitors     immunotherapy    

Using sound Clinical Paths and Diagnosis-related Groups (DRGs)-based payment reform to bring benefits to patient care: A case study of leukemia therapy

Zhi-Ruo ZHANG PhD, Jian-Qing MI MD, Zhao-Jun WEN MA, Sai-Juan CHEN MD, PhD, Zhu CHEN PhD, Long-Jun GU MD, Jing-Yan TANG MD, PhD, Shu-Hong SHEN MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 8-15 doi: 10.1007/s11684-010-0018-5

Abstract: Treatments of acute promyelocytic leukemia at Rui-Jin Hospital, and childhood acute lymphoblastic leukemia

Keywords: healthcare reform     diagnosis-related groups     clinical paths     comparative effectiveness analysis     acute promyelocyticleukemia     childhood acute lymphoblastic leukemia    

Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia

Ching-Hon Pui

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 1-9 doi: 10.1007/s11684-015-0381-3

Abstract:

With the cure rate of childhood acute lymphoblastic leukemia (ALL) approaching 90%, further improvement

Keywords: pharmacogenomics     acute lymphoblastic leukemia     genomics     pharmacogenetics    

expression pattern of mutations coordinated by target repression and promoter hypermethylation in acute

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 627-636 doi: 10.1007/s11684-020-0815-4

Abstract: Its dysfunction, caused by either fusions or mutations, is frequently reported in acute myeloid leukemia

Keywords: RUNX1     gene mutation     acute myeloid leukemia     transcriptional repression     DNA methylation    

Risk factors of prognosis after acute kidney injury in hospitalized patients

Sasa Nie, Zhe Feng, Lihua Xia, Jiuxu Bai, Fenglin Xiao, Jian Liu, Li Tang, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 393-402 doi: 10.1007/s11684-017-0532-9

Abstract:

The risk factors, especially laboratory indicators, of prognosis after acute kidney injury (AKI) remain

Keywords: acute kidney injury     risk factors     prognosis    

Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 302-305 doi: 10.1007/s11684-011-0145-7

Abstract: A treatment method based on drainage via retroperitoneal laparoscopy was adopted for 15 severe acute

Keywords: severe acute pancreatitis (SAP)     laparoscope     retroperitoneal drainage     treatment    

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 442-458 doi: 10.1007/s11684-021-0877-y

Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is one of the most dangerous hematological malignancies,

Keywords: T-cell acute lymphoblastic leukemia     HDAC inhibitor     chidamide     NOTCH1     MYC     ubiquitination    

Title Author Date Type Operation

Current treatment strategy of acute promyelocytic leukemia

Jianqing Mi

Journal Article

Predictive values of plasma TNFα and IL-8 for intracranial hemorrhage in patients with acute promyelocytic

Journal Article

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Journal Article

BRD4 interacts with PML/RARα in acute promyelocytic leukemia

Qun Luo, Wanglong Deng, Haiwei Wang, Huiyong Fan, Ji Zhang

Journal Article

network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acutepromyelocytic leukemia

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acutepromyelocytic leukemia

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article

upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acutepromyelocytic leukemia

Dan Huang, Yan Yang, Jian Sun, Xiaorong Dong, Jiao Wang, Hongchen Liu, Chengquan Lu, Xueyu Chen, Jing Shao, Jinsong Yan

Journal Article

Molecular pathogenesis of acute myeloid leukemia: A diverse disease with new perspectives

Felicitas THOL, Arnold GANSER

Journal Article

Precision medicine in acute lymphoblastic leukemia

Ching-Hon Pui

Journal Article

Using sound Clinical Paths and Diagnosis-related Groups (DRGs)-based payment reform to bring benefits to patient care: A case study of leukemia therapy

Zhi-Ruo ZHANG PhD, Jian-Qing MI MD, Zhao-Jun WEN MA, Sai-Juan CHEN MD, PhD, Zhu CHEN PhD, Long-Jun GU MD, Jing-Yan TANG MD, PhD, Shu-Hong SHEN MD, PhD,

Journal Article

Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia

Ching-Hon Pui

Journal Article

expression pattern of mutations coordinated by target repression and promoter hypermethylation in acute

Journal Article

Risk factors of prognosis after acute kidney injury in hospitalized patients

Sasa Nie, Zhe Feng, Lihua Xia, Jiuxu Bai, Fenglin Xiao, Jian Liu, Li Tang, Xiangmei Chen

Journal Article

Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Journal Article

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Journal Article